We hit a huge milestone today, thanks to the wonderful work of our rocking electrical and computer science engineering intern, Camila Dorin: we now have a stand-alone application (pictured here working on my MacAir) that can conduct the analysis we need to distinguish epithelial cancer using a simple web cam and our proprietary lens.
The simple application enables us to view a region of interest (here, the region is a nevus or mole on my forearm) using different illuminations. This picture is viewing my nevus using green light illumination, which is how clinicians view the cervix during colposcopy. To acquire this image we used a non-HD Microsoft webcam, and a compound lens assembled from off-the-shelf parts (thank you, Thorlabs!).
The magic happens when we switch on PolDiff, and enable single camera polarized difference imaging, to isolate the superficial layer where the cancers grow. With this, we are building upon insights from the great work led by our Scientific Advisor, Prof. Steven L. Jacques, and Prof. Jessica Ramella-Roman, to show how cancer presents itself differently than other lesions or epithelial conditions. In addition, we can conduct basic spectral measurements of the three layers of the epithelium simultaneously, and then analyze them in parallel, enabling a much richer data set with which to determine whether or not the region contains a cancerous growth.
Next step: an android application. This will enable us to take this power on the road - and most importantly, to enable the point-of-care diagnosis of potential cancers for people without access to advanced medical facilities, but who do have access to a mobile phone.
How to Defeat Cervical Cancer
This blog reflects the lessons our team learns on our quest to defeat cervical cancer.